What Are the Benefits of Durolane Injections for Joint Pain Relief?

Author: Raj Gandhi

Date: 29-01-2025

Last Reviewed: 14-08-2026

Durolane is a hyaluronic acid injection that restores natural lubrication to a painful joint, commonly used for osteoarthritis in the knee or shoulder. A single injection often provides relief within days that can last up to a year, with minimal recovery time since it's a non-surgical, in-office procedure. It's generally considered for people with mild to moderate osteoarthritis who want to manage pain and delay or avoid surgery, particularly if oral medication hasn't worked well or isn't suitable.

What Is Durolane?

When you have joint pain, it can be debilitating. You may have been told the same story again and again: that "there isn't much you can do about it," or that you should "just rest and wait for the pain to go away." Or you've visited your GP and they have hooked you up with some powerful painkillers that will mask the pain, but as soon as the medication runs out, you are back at the doctor's office to get a repeat prescription in a never-ending cycle.

You may not know where to turn, but I want to offer you advice and solutions that will probably go against what you might have been told elsewhere. I want to help get you active again, enjoying life and doing the things that you were doing before the pain struck.

One of the powerful pain-busting tools I have at my disposal is Durolane, which can offer significant relief for people who are suffering from joint pain, be it from osteoarthritis or just general wear and tear.

Durolane is a hyaluronic acid treatment that I inject directly into a painful joint using ultrasound guidance. Hyaluronic acid occurs naturally in the body and helps to lubricate and cushion your joints. When you have osteoarthritis, the amount of lubrication in your joints decreases significantly, causing pain, bone rubbing and inflammation. When you opt for a Durolane treatment, the levels of hyaluronic acid are returned to their expected levels and this provides natural cushioning, giving you pain relief, reducing swelling and improving your ability to use the affected joint.

What Are the Many Benefits of Durolane?

Effective Pain Relief

A Durolane supplement injection can provide you with significant pain relief. It does this by replenishing the hyaluronic acid in the joint, reducing friction and wear and tear on the cartilage. My clients tell me that they have immediate relief following the injection, and the effects of one injection can last upwards of 12 months. The benefit of this is that it can help you manage any chronic pain while staving off unnecessary surgery.

Improved Joint Mobility

When you have a painful joint, it naturally gets stiff and you have limited movement, which affects you in all your daily activities, such as sitting, standing, walking, getting out of bed, getting dressed, tying your shoes etc. The hyaluronic acid injection helps restore the lubrication in the joint, reducing your pain and giving you more mobility and flexibility. As your pain decreases, your movement improves and you are often able to regain a large range of motion, significantly improving your quality of life.

Minimally Invasive Treatment

This is not a surgical procedure, and I carry out Durolane injection treatment right here at Relive Physiotherapy. In total, you will be in and out in less than an hour. The recovery time is minimal, and you can resume normal activities within a day or two, with only mild discomfort or swelling at the injection site. This makes Durolane an excellent treatment for those who want relief from their pain without the risks and recovery time following surgery.

Long-Lasting Relief

You can get pain relief almost immediately when you opt for a Durolane injection. This relief can last for many months, and in some cases, up to or even exceeding 1 year. However, there are many factors that can influence how long the relief from this treatment can last, so I can't put an accurate figure on how long you'll feel the positive benefits. However, one thing is sure: it reduces the need for longer-term treatments, which can be costlier in the long run. You can manage your joint pain in a way that is more suited to your lifestyle rather than having to succumb to the pain that ends up ruling your life.

Fewer Side Effects Compared to Oral Medications

If you have been taking tablets to manage your pain, then you will be familiar with the side effects that often come with this type of treatment: stomach pain, ulcers and problems with your kidneys. Durolane is an injection that takes place directly into the area around the joint, so this greatly reduces the chance of any unwanted side effects. This is a much safer alternative solution for anybody who can't take oral medicine or is worried about any potential side effects and complications.

Promotes Joint Health

In addition to providing pain relief, Durolane injections may help improve the overall health of your joint. Hyaluronic acid helps to nourish and protect your cartilage, slowing down the wear and tear process of osteoarthritis. By restoring the natural properties of the joint fluid, Durolane may support the healing of damaged tissue and contribute to long-term joint health.

A Non-Surgical Option for Joint Care

If you are thinking about surgery on your painful joint or looking to delay surgery, Durolane offers a non-surgical option to manage your pain and improve the function of your joint. I find it's great for people with mild to moderate osteoarthritis and people who have pain, but where surgery is not yet necessary.

Who Can Benefit from Durolane Injections?

I most commonly give Durolane injections to people who suffer from osteoarthritis, typically in the knee and shoulder (but I do them in other joints too). I also see people who have injuries at their joints, general wear and tear, and conditions that affect the quality and quantity of synovial fluid (lubricator) in the joint. If you are suffering from chronic pain in your joints and none of the other treatments that you have tried have worked, then it might be worth giving Durolane a try.

How Can You Relieve Your Joints with Durolane?

If you are suffering from joint pain or osteoarthritis, then Durolane is an effective and perfectly non-invasive treatment for you. It can help with your pain, the mobility of your joints and has minimal side effects, which means that you can go about your life as you did before the pain got too much.

If you aren't sure about whether Durolane could be for you, get in touch with the team at Relive Physiotherapy and have a chat with me. I'll help you decide what's best by talking you through the different options available to you.

Frequently Asked Questions

How long does a Durolane injection last?

Relief can last upwards of 12 months in some cases, though this varies from person to person depending on individual factors. Many people notice relief almost immediately after the injection.

Is a Durolane injection painful or invasive?

No. It's a minimally invasive, in-office procedure that typically takes under an hour, with only mild discomfort or swelling at the injection site afterwards. Most people can resume normal activities within a day or two.

Who is Durolane suitable for?

It's most commonly used for people with mild to moderate osteoarthritis, particularly in the knee or shoulder, as well as those with joint wear and tear or reduced synovial fluid, especially where surgery isn't yet necessary.

Does Durolane have fewer side effects than oral pain medication?

Because it's injected directly into the joint rather than taken orally, it generally carries a lower risk of side effects like stomach irritation or kidney issues compared to long-term oral pain medication.

Can Durolane help me avoid or delay joint surgery?

For many people, yes. It's often used as a non-surgical option to manage pain and improve joint function, which can help delay or reduce the need for surgery, particularly in earlier-stage osteoarthritis.

About the Author:

Raj Gandhi

Lead Physiotherapist & Independent Non-Medical Prescriber

Raj Gandhi is a Chartered Physiotherapist and co-founder of Relive Physiotherapy, with over 20 years' specialist experience in Orthopaedics, Sports Injuries, and Musculoskeletal Medicine.

He holds a Master's degree in Sports Physiotherapy, a Postgraduate Diploma in Orthopaedic Medicine and Injection Therapy, and a Postgraduate Certificate in Independent Prescribing. Raj has a particular interest in treating back and neck pain, along with a wide range of sports injuries, and has worked as a Physiotherapist for the Commonwealth Games team. He spent over 10 years in the NHS before leaving to establish Relive Physiotherapy and is widely respected among colleagues for his expertise in Injection Therapy and his hands-on, manual approach to treatment.

Raj is a member of the Association of Chartered Physiotherapists in Orthopaedic Medicine and Injection Therapy (ACPOMIT), the Acupuncture Association of Chartered Physiotherapists (AACP), and the Association of Chartered Physiotherapists in Sports Medicine (ACPSEM). He also mentors the physiotherapy team at Relive, regularly leading training and supporting their ongoing development.

Outside the clinic, Raj is a father to two girls and enjoys playing tennis, listening to audiobooks, and photography.